Novel method for microencapsulation of eutectic hydrated salt

Protein conformation in pure and hydrated deep eutectic solvents.

Deep eutectic solvents (DES) have recently been postulated as possible environments where protein structure may be preserved in the absence of water. Here we present our results towards understanding protein conformation in choline chloride-based DES and mixtures with water. Lysozyme and bovine serum albumin have been investigated by means of circular dichroism and small-angle neutron scattering.

Raman mapping in the elucidation of solid salt eutectic and near eutectic structures†

The distribution of the different components of solidified eutectic or near-eutectic salt mixtures (eutectics) was examined by use of Raman microscope mapping of the structures formed when these melts were slowly cooled. Seven binary and one ternary system were investigated. In most cases the component crystallized phases consisted of roughly rounded areas of about 0.5–5 μm across, the areas al...

Ultrasonic Atomisation: a Novel Method for Microencapsulation of Proteins and Peptides

Microencapsulation as a novel delivery method for the potential antidiabetic drug, Probucol

INTRODUCTION In previous studies, we successfully designed complex multicompartmental microcapsules as a platform for the oral targeted delivery of lipophilic drugs in type 2 diabetes (T2D). Probucol (PB) is an antihyperlipidemic and antioxidant drug with the potential to show benefits in T2D. We aimed to create a novel microencapsulated formulation of PB and to examine the shape, size, and che...

Catalytic Gasification of Coal using Eutectic Salt Mixtures